Trends in warfarin use and its associations with thromboembolic and bleeding rates in a population with atrial fibrillation between 1996 and 2011
PLoS ONE2018Vol. 13(3), pp. e0194295–e0194295
Citations Over TimeTop 16% of 2018 papers
Peter W Hansen, T S G Sehested, Emil Loldrup Fosbøl, Christian Torp‐Pedersen, Lars Køber, Charlotte Andersson, Gunnar Gislason
Abstract
Warfarin use increased by nearly a 3-fold between 1996 and 2011. During the same period, thromboembolic events declined by a third and bleeding increased by a fifth, suggesting a beneficial effect associated with higher warfarin use. Notably, a small decline in thromboembolic events and increase in bleeding events was observed for the untreated population, suggesting a changing risk profile of AF patients.
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