Investigation of the association between serum uric acid levels and HEART risk score in patients with acute coronary syndrome

Citations Over TimeTop 10% of 2022 papers

Abstract

The association between uric acid (UA) and cardio-metabolic conditions has been recognized for a long time. However, recently, a body of evidence has highlighted the independent role of UA in a series of conditions, including renal and cardiovascular diseases. In this light, data regarding the prognostic role of UA in acute coronary syndrome (ACS) is scarce. A total number of 100 patients, 59 males and 41 females, diagnosed with ACS were recruited in this study. At the time of admission to the hospital, the serum level of UA was measured. In addition, the HEART score was calculated based on each patients' profile. Participants were on average 61.37 ± 12.08 years old. The most prevalent risk factors were hypertension (48%), a history of coronary artery disease (40%), and diabetes mellitus (33%). The average serum level of UA was 5.81 ± 1.81 mg/dl, and the calculated HEART score had a median of six (minimum of two and maximum of ten). A positive yet statistically insignificant correlation was found between the measured UA level and the calculated HEART score (R = 0.375, p = 0.090). However, further studies with larger sample size are required to assess the direct association of UA level with major adverse cardiac events in patients with cardiovascular disease.

Related Papers

• → Relationship between Changes in Components Associated with Metabolic Syndrome and Disappearance, or Remission, of Metabolic Syndrome during 1 Year(2012)5 cited
• → Study of non-alcoholic fatty liver disease in metabolic syndrome(2018)3 cited
• A study on metabolic syndrome in patients with Psoriasis(2021)
• → STUDIES IN THE URIC ACID METABOLISM OF CHILDREN(1924)12 cited
• Editorial Note on Metabolic Syndrome.(2021)