Assessment of dynamic changes in cerebral autoregulation
Citations Over Time
Abstract
Cerebral autoregulation (CA) is a control mechanism that adjusts cerebral vasomotor tone in response to changes in arterial blood pressure (ABP) to ensure a nearly constant cerebral blood flow. Patient treatment could be optimized if CA monitoring were possible. Whereas the concept of static CA assessment is simply based on comparison of mean values obtained from two stationary states (e.g., before and after a pressure change), the evaluation of dynamic CA is more complex. Among other methods, moving cross-correlation analysis of slow waves in ABP and cerebral blood flow velocity (CBFV) seems to be appropriate to monitor CA quasi-continuously. The calculation of an "instantaneous transfer function" between ABP and CBFV oscillations in the low-frequency band using the Wigner-Ville distribution may represent an acceptable compromise in time-frequency resolution for continuous CA monitoring.
Related Papers
- → Regulatory Mechanisms of Cerebral Blood Flow During Exercise(2009)137 cited
- → Functional TCD: Regulation of Cerebral Hemodynamics - Cerebral Autoregulation, Vasomotor Reactivity, and Neurovascular Coupling(2014)51 cited
- → Physiology and dynamics of the cerebral circulation(1990)
- → Cerebral Autoregulation. Regional Cerebral Blood Flow and Cardiohemodynamic Measurements(1975)
- → Investigating Cerebral Autoregulation in Traumatic Brain Injury via Simultaneous Measurements of Intracranial Pressure, Arterial Blood Pressure and relative Cerebral Blood Flow(2023)