PLASMA GROWTH HORMONE AND SERUM PHOSPHORUS CONCENTRATIONS IN RELATION TO THE MENOPAUSE AND TO OESTROGEN THERAPY

Citations Over Time

Abstract

SUMMARY Plasma human growth hormone (HGH) and serum phosphorus concentrations were measured during the fasting ambulatory state in middleaged men, pre- and postmenopausal women and postmenopausal women who had been taking 20–40 μg mestranol daily for 1–3 years. The mean plasma HGH concentrations were consistently higher in the women than they were in the men, there was little difference between the mean values for pre- and postmenopausal women, and the mestranoltreated women had significantly higher mean values than the untreated postmenopausal women. The mean serum phosphorus concentration was significantly higher after menopause and was significantly lower in those women on long-term lowdose mestranol therapy. A significant direct correlation was found between serum phosphorus and plasma HGH concentrations in untreated postmenopausal women. It is suggested that the postmenopausal relative hyperphosphataemia is consistent with increased HGH activity.

Related Papers

• → Growth hormone binding protein in the rat: effects of gonadal steroids.(1993)59 cited
• → Exogenous Glucocorticoids and a High-Fat Diet Cause Severe Hyperglycemia and Hyperinsulinemia and Limit Islet Glucose Responsiveness in Young Male Sprague-Dawley Rats(2013)47 cited
• → The Paraventricular Nucleus of the Hypothalamus Has a Major Role in Thyroid Hormone Feedback Regulation of Thyrotropin Synthesis and Secretion(1990)53 cited
• → The Effect of Fasting on Tissue Cyclic cAMP and Plasma Glucagon in the Obese Hyperglycemic Mouse(1975)39 cited
• → Modulation of Adipoinsular Axis in Prediabetic Zucker Diabetic Fatty Rats by Diazoxide(2004)39 cited