IDH mutation and MGMT promoter methylation in glioblastoma: results of a prospective registry
Oncotarget2015Vol. 6(38), pp. 40896–40906
Citations Over TimeTop 10% of 2015 papers
Pei Yang, Wei Zhang, Yinyan Wang, Xiaoxia Peng, Baoshi Chen, Xiaoguang Qiu, Guilin Li, Shouwei Li, Chenxing Wu, Kun Yao, Wenbin Li, Wei Yan, Jie Li, Yongping You, Clark C. Chen, Tao Jiang
Abstract
Our study demonstrates IDH mutation and MGMT promoter methylation status independently associate with favorable outcome in TMZ+RT treated glioblastoma patients. However, these biomarkers differentially impact clinical TMZ response.
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