Paeonol protects endotoxin-induced acute kidney injury: potential mechanism of inhibiting TLR4-NF-κB signal pathway
Oncotarget2016Vol. 7(26), pp. 39497–39510
Citations Over TimeTop 10% of 2016 papers
Huaying Fan, Qi Dong, Chen Yu, Feng Zhao, Tao Liu, Zuo-Kai Zhang, Mingyan Yang, Leiming Zhang, Daquan Chen, Yuan Du
Abstract
These results indicated that paeonol has protective effects on endotoxin-induced kidney injury. The mechanisms underlying such effects are associated with its successfully attenuate inflammatory and suppresses TLR4 and NF-κB signal pathway. Therefore, paeonol has great potential to be a novel and natural product agent for treating AKI or septic-AKI.
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