Chondrosarcoma of Bone
Citations Over TimeTop 10% of 1999 papers
Abstract
Although the data are suggestive, with the numbers available for study we could not detect a significant difference in the rates of pulmonary metastasis and death between the patients who had a grade-3 lesion and those who had a grade-3 lesion that was also dedifferentiated. However, the interval between diagnosis and death was 32+/-22.8 months for the patients who had a grade-3 lesion compared with 5+/-3.7 months for those who had a grade-3 lesion that was also dedifferentiated (p < 0.001). Overall, patients who had had a resection with wide margins (margins extending outside the reactive zone) had a longer duration of survival than did those who had had a so-called marginal resection (margins extending outside the tumor but within the reactive zone) or an intralesional resection (margins within the lesion) (p < 0.04). Adjunctive chemotherapy or radiation, or both (which, it must be noted, was used, without a protocol, in a relatively small number of patients), after an intralesional resection, for recurrent disease, or for distant metastasis did not appear to alter the outcome.
Related Papers
- Major exarticulations for malignant neoplasms of the extremities: interscapulothoracic amputation, hip-joint disarticulation, and interilio-abdominal amputation; a report of end results in 228 cases.(1956)
- → Amputation for Tumor of the Upper Arm(1983)11 cited
- Syme's ankle disarticulation: the transmalleolar amputation.(1997)
- → Amputation at the Knee-Joint by Disarticulation; with Remarks on Amputation of the Leg by Lateral Flaps(1886)
- → Amputation(2019)