<p>RRAD suppresses the Warburg effect by downregulating ACTG1 in hepatocellular carcinoma</p>
OncoTargets and Therapy2019Vol. Volume 12, pp. 1691–1703
Citations Over Time
Yingcai Yan, Hao Xu, Linshi Zhang, Xiaohu Zhou, Xiaohui Qian, Jiarong Zhou, Yu Huang, Wenhao Ge, Weilin Wang
Abstract
We have shown that RRAD exhibits a tumor-suppressing role in HCC by downregulating glucose metabolism and ACTG1 expression, thus lowering cell proliferation, arresting the cell cycle, and increasing apoptosis. These findings indicate that ACTG1 may act as a downstream effector of RRAD and open a new avenue for potential HCC treatment.
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