Utility of blood procalcitonin concentration in the management of cancer patients with infections
OncoTargets and Therapy2016Vol. 9, pp. 469–469
Citations Over TimeTop 19% of 2016 papers
Katarzyna Niemirowicz, Bonita Durnaś, Marzena Wątek, Tomasz Wollny, Robert Bucki, Stanisław Góźdż, Michał Marzec
Abstract
Diagnosis of infections in cancer patients is usually problematic since differentiating between infection and fever of unknown origin is often a considerable clinical challenge. In general, increase concentration of blood procalcitonin (PCT) is associated with severe bacterial infection. PCT with an optimal cutoff level of 0.5 ng/mL seems to be the most helpful biochemical parameter in detecting severe infections, mainly bloodstream infection, in patients with hematological cancers. In all clinical situations, the elevated level of PCT should be carefully analyzed, always with a thorough physical examination and an appropriate microbiological assessment.
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