Solitary Fibrous Tumor of the Thoracic Spinal Cord-Case Report-
Citations Over Time
Abstract
A 63-year-old woman presented with a rare case of primary solitary fibrous tumor (SFT) occurring in the extramedullary thoracic spinal cord. T1-weighted magnetic resonance (MR) imaging showed the tumor as a mildly hypointense area with homogeneous enhancement by gadolinium. T2-weighted MR imaging showed a hypointense mass with peritumoral edema. The tumor arose from one of the posterior spinal roots, with no attachment to the dura. The tumor was clearly circumscribed from the surrounding cord tissue and easily removed. Histological examination showed the tumor predominantly consisted of spindle cells separated by abundant collagen matrix fibers. Tumor cells were strongly positive for vimentin and CD34, but negative for glial fibrillary acidic protein, S-100 protein, epithelial membrane antigen, myelin basic protein, and keratin. SFT should be considered in the differential diagnosis of spindle cell central nervous system neoplasms, although SFT is extremely rare in the spinal cord.
Related Papers
- → M�ller cells in detached human retina express glial fibrillary acidic protein and vimentin(1990)91 cited
- → Co‐expression of GFAP and vimentin in astrocytes proliferating in response to injury in the mouse cerebral hemisphere. A combined autoradiographic and double immunocytochemical study(1993)83 cited
- → Expression of Glial Fibrillary Acidic Protein in Rat C6 Glioma Relates to Vimentin and Is Independent of Cell‐Cell Contact(1987)39 cited
- Vimentin and glial fibrillary acidic protein expression in relation to neoplastic cell differentiation in glial tumors.(1992)
- → Glial filaments in the subcutaneous tumors of mouse glioma clones differently expressing glial fibrillary acidic protein(1987)2 cited