Detecting and Filtering Immune-Related Adverse Events Signal Based on Text Mining and Observational Health Data Sciences and Informatics Common Data Model: Framework Development Study
JMIR Medical Informatics2020Vol. 8(6), pp. e17353–e17353
Citations Over TimeTop 15% of 2020 papers
Yue Yu, Kathryn J. Ruddy, Aaron S. Mansfield, Nansu Zong, Andrew Wen, Shintaro Tsuji, Ming Huang, Hongfang Liu, Nilay D. Shah, Guoqian Jiang
Abstract
We demonstrated that our approach is effective for irAE signal detection and filtration. Moreover, our CDM-based framework could facilitate adverse drug events detection and filtration toward the goal of next-generation pharmacovigilance that seamlessly integrates electronic health record data for improved signal detection.
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