Biomarkers in breast cancer
Jugoslovenska medicinska biohemija2006Vol. 25(4), pp. 355–361
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Sladjana Filipovic, Aleksandra Filipović, Ivica Pejcic, Vrbić Svetislav, Zorica Stanojević, Ivana Mišić
Abstract
Breast cancer is a disease characterized by abnormal growth and development of nor mal breast tissue. When the growth and development of a normal cell no longer obey biological control mechanisms, tumor cells begin to appear. An understanding of normal biological processes relating to cell growth, such as the cell cycle, angiogenesis, and apoptosis, and of other abnormal processes, such as neo-plastic transformation, tumor progression, and metastasis, would aid not only in identifying tumor markers, but also in determining the best uses of these tumor markers for diagnosis and treatment of patients with cancer. Biomarkers are improving our understanding of the biology and management of breast cancer.
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