A Critique of Clinical Equipoise: Therapeutic Misconception in the Ethics of Clinical Trials
The Hastings Center Report2003Vol. 33(3), pp. 19–19
Citations Over TimeTop 1% of 2003 papers
Abstract
A predominant ethical view holds that physician-investigators should conduct their research with therapeutic intent. And since a physician offering a therapy wouldn't prescribe second-rate treatments, the experimental intervention and the best proven therapy should appear equally effective. "Clinical equipoise" is necessary. But this perspective is flawed. The ethics of research and of therapy are fundamentally different, and clinical equipoise should be abandoned.
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