Effects of Physical Activity and Weight Loss on Skeletal Muscle Mitochondria and Relationship With Glucose Control in Type 2 Diabetes
Diabetes2007Vol. 56(8), pp. 2142–2147
Citations Over TimeTop 1% of 2007 papers
Frederico G. S. Toledo, Elizabeta V. Menshikova, Vladimir B. Ritov, Koichiro Azuma, Žofia Rádiková, James P. DeLany, David E. Kelley
Abstract
Intensive short-term lifestyle modifications can restore mitochondrial content and functional capacity in skeletal muscle in type 2 diabetic patients. The improvement in the oxidative capacity of skeletal muscle may be a key component mediating salutary effects of lifestyle interventions on hyperglycemia and insulin resistance.
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