Essential Role of Mitochondrial Function in Adiponectin Synthesis in Adipocytes
Diabetes2007Vol. 56(12), pp. 2973–2981
Citations Over TimeTop 10% of 2007 papers
Eun Hee Koh, Joong‐Yeol Park, Hye‐Sun Park, Min Jae Jeon, Je Won Ryu, Mina Kim, Sun Young Kim, Min‐Seon Kim, Seung‐Whan Kim, In Sun Park, Jang H. Youn, Ki‐Up Lee
Abstract
Mitochondrial function is linked to adiponectin synthesis in adipocytes, and mitochondrial dysfunction in adipose tissue may explain decreased plasma adiponectin levels in obesity. Impaired mitochondrial function activates a series of mechanisms involving ER stress, JNK, and ATF3 to decrease adiponectin synthesis.
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