Acute Diabetes Moderates Trafficking of Cardiac Lipoprotein Lipase Through p38 Mitogen-Activated Protein Kinase–Dependent Actin Cytoskeleton Organization
Diabetes2007Vol. 57(1), pp. 64–76
Citations Over TimeTop 11% of 2007 papers
Minsuk Kim, Girish Kewalramani, Prasanth Puthanveetil, Vivian Lee, Ujendra Kumar, An Ding, Ashraf Abrahani, Brian Rodrigues
Abstract
We propose that AMPK recruitment of LPL to the cardiomyocyte surface (which embraces p38 MAPK activation and actin cytoskeleton polymerization) represents an immediate compensatory response by the heart to guarantee fatty acid supply when glucose utilization is compromised.
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