AMP-Activated Protein Kinase Regulates GLUT4 Transcription by Phosphorylating Histone Deacetylase 5
Diabetes2008Vol. 57(4), pp. 860–867
Citations Over TimeTop 1% of 2008 papers
Sean L. McGee, Bryce J. W. van Denderen, Kirsten F. Howlett, Janelle P. Mollica, Jonathan D. Schertzer, Bruce E. Kemp, Mark Hargreaves
Abstract
These data reveal a signal transduction pathway linking cellular energy charge to gene transcription directed at restoring cellular and whole-body energy balance and provide new therapeutic targets for the treatment and management of insulin resistance and type 2 diabetes.
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