Therapeutic Potential of Peroxisome Proliferators–Activated Receptor-α/γ Dual Agonist With Alleviation of Endoplasmic Reticulum Stress for the Treatment of Diabetes
Diabetes2007Vol. 57(3), pp. 737–745
Citations Over TimeTop 10% of 2007 papers
Kyu Lee Han, Joo Sun Choi, Jae‐Young Lee, Jihyun Song, Myung Kuk Joe, Myeong Ho Jung, Jae‐Kwan Hwang
Abstract
Macelignan enhanced insulin sensitivity and improved lipid metabolic disorders by activating PPARalpha/gamma and attenuating ER stress, suggesting that it has potential as an antidiabetes agent for the treatment of type 2 diabetes.
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