Separate Impact of Obesity and Glucose Tolerance on the Incretin Effect in Normal Subjects and Type 2 Diabetic Patients
Diabetes2007Vol. 57(5), pp. 1340–1348
Citations Over TimeTop 10% of 2007 papers
Elza Muscelli, Andrea Mari, A Casolaro, Stefania Camastra, Giuseppe Seghieri, Amalia Gastaldelli, Jens J. Holst, Ele Ferrannini
Abstract
Potentiation of insulin secretion, glucose sensing, glucagon-like peptide-1 release, and glucagon suppression are physiological manifestations of the incretin effect. Glucose tolerance and obesity impair the incretin effect independently of one another.
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