Treatment of Obese Diabetic Mice With a Heme Oxygenase Inducer Reduces Visceral and Subcutaneous Adiposity, Increases Adiponectin Levels, and Improves Insulin Sensitivity and Glucose Tolerance
Diabetes2008Vol. 57(6), pp. 1526–1535
Citations Over TimeTop 10% of 2008 papers
Ming Li, Dong Hyun Kim, Peter L. Tsenovoy, Stephen J. Peterson, Rita Rezzani, Luigi Fabrizio Rodella, Wilbert S. Aronow, Susumu Ikehara, Nader G. Abraham
Abstract
This study provides strong evidence for the existence of an HO-1-adiponectin regulatory axis that can be manipulated to ameliorate the deleterious effects of obesity and the metabolic syndrome associated with cardiovascular disease and diabetes.
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