Role of Central Nervous System Glucagon-Like Peptide-1 Receptors in Enteric Glucose Sensing
Diabetes2008Vol. 57(10), pp. 2603–2612
Citations Over TimeTop 10% of 2008 papers
Claude Knauf, Patrice D. Cani, Donghoon Kim, Miguel A. Iglesias, Chantal Chabo, Aurélie Waget, André Colom, Sophie Rastrelli, Nathalie M. Delzenne, Daniel J. Drucker, Randy J. Seeley, Rémy Burcelin
Abstract
We conclude that the gut-glucose sensor modulates peripheral glucose metabolism through a nutrient-sensitive mechanism, which requires brain GLP-1Rc signaling and is impaired during diabetes.
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