Metabolomic Profiling of Fatty Acid and Amino Acid Metabolism in Youth With Obesity and Type 2 Diabetes
Diabetes Care2012Vol. 35(3), pp. 605–611
Citations Over TimeTop 10% of 2012 papers
Stephanie J. Mihalik, Sara F. Michaliszyn, Javier de las Heras, Fida Bacha, SoJung Lee, Donald H. Chace, Victor DeJesus, Jerry Vockley, Silva Arslanian
Abstract
These metabolomics results, together with the increased rates of in vivo FOX, are not supportive of defective fatty acid or amino acid metabolism in obesity and type 2 diabetes in youth. Such observations are consistent with early adaptive metabolic plasticity in youth, which over time-with continued obesity and aging-may become dysfunctional, as observed in adults.
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