Quantitative Susceptibility Mapping Suggests Altered Brain Iron in Premanifest Huntington Disease
American Journal of Neuroradiology2015Vol. 37(5), pp. 789–796
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Jiri M.G. Van Bergen, Jun Hua, Paul G. Unschuld, Issel Anne L. Lim, Craig Jones, Russell L. Margolis, Christopher A. Ross, Peter C.M. van Zijl, Xu Li
Abstract
The significant magnetic susceptibility differences between subjects with premanifest Huntington disease and controls and their correlation with genetic burden scores indicate the potential use of magnetic susceptibility as a biomarker of disease progression in premanifest Huntington disease.
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