Four Common Late-Life Cognitive Trajectories Patterns Associate with Replicable Underlying Neuropathologies
Journal of Alzheimer s Disease2021Vol. 82(2), pp. 647–659
Citations Over TimeTop 11% of 2021 papers
Shama D. Karanth, Frederick A. Schmitt, Peter T. Nelson, Yuriko Katsumata, Richard J. Kryscio, David W. Fardo, Jordan P. Harp, Erin L. Abner
Abstract
Cognitive trajectories associated strongly with neuropathology, particularly Braak NFT stage. High frequency of multiple pathologies in trajectories with cognitive decline suggests dementia treatment and prevention efforts must consider multiple diseases simultaneously.
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