A review of the natural history and epidemiology of multiple sclerosis: implications for resource allocation and health economic models

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Abstract

Despite intensive epidemiological investigation over many decades in many parts of the world, the geographical distribution and the true prevalence and incidence of MS remain uncertain. In recent years a clearer understanding of the distribution of MS has emerged, though debate continues and uncertainties remain. Variations in prevalence have Chapter 1 * From a cross section of 1099 MS patients at final review From 363 patients in a prevalence survey From 780 patients attending University of British Columbia MS Clinic From Veteran's Administration hospital admissions (A) and World War 2 veterans (B) according to Kurtzke From 301 (of 441) patients in a prevalence survey ** From 254 patients in a cohort study n/k, not known * No relapses or progression of disability RR disease without or with progression of disability unresolved 6 months after a relapse

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