Different Pharmacological Properties of GLUT9a and GLUT9b: Potential Implications in Preeclampsia
Cellular Physiology and Biochemistry2019Vol. 53(3), pp. 508–517
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Bernhard Lüscher, Daniel Surbek, Benjamin Clémençon, Xiao Huang, Christiane Albrecht, Camilla Marini, Matthias A. Hediger, Marc Baumann
Abstract
To the best of our knowledge, this is the first study showing that the N-terminal domain of hGLUT9a has a unique regulatory function and the potential to interact with small negatively charged ions like iodide. These findings may have significant implications in our understanding of hyperuricemia-associated diseases, specifically during pregnancy.
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