Sphingobium Olei Peritonitis: Peritoneal Dialysis in Turmoil?

Peritoneal Dialysis International2013Vol. 33(1), pp. 102–103

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N.M. Ruiter, Trijntje T. Cnossen, Remko Bakker, P.J.H. van Keulen

Abstract

PDIBoth patients were fortunate in that they did not develop peritonitis as a result of their PD exit-site or tunnel infection, and they were able to retain the Tenckhoff catheter.no further PD exit-site or tunnel infections with the same organism were observed in either patient after treatment with ofloxacin otic solution, oral antibiotics, and cuff-shaving. DISCUSSIOn AnD COnCLUSIOnSDespite exit-site care, PD patients experience exit-site and tunnel infections (3-5).The standard of care for PD exit-site and tunnel infections is administration of oral antibiotics for 2 -3 weeks (1).Our novel approach using ofloxacin otic solution 0.3% reached the PD exit-site or catheter tunnel and provided therapeutic antibiotic concentrations at the site of infection (6).Ofloxacin otic solution is a sterile aqueous solution normally used to treat otitis externa caused by Escherichia coli, P. aeruginosa, and S. aureus (7).We propose that ofloxacin otic solution be used as adjuvant antibiotic therapy for severe PD exit-site and tunnel infections with P. aeruginosa, MrSA, Klebsiella pneumoniae, or a. xylosoxidans.Prompt treatment of PD exit-site and tunnel infections prevents progression to peritonitis.A lower peritonitis rate allows patients to continue treatment with PD.In summary, ofloxacin otic solution 0.3% may be used as adjuvant antibiotic therapy for PD exit-site and tunnel infections.

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Abstract

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