Investigation of Macrophage Polarization Using Bone Marrow Derived Macrophages

Citations Over TimeTop 10% of 2013 papers

Abstract

The article describes a readily easy adaptive in vitro model to investigate macrophage polarization. In the presence of GM-CSF/M-CSF, hematopoietic stem/progenitor cells from the bone marrow are directed into monocytic differentiation, followed by M1 or M2 stimulation. The activation status can be tracked by changes in cell surface antigens, gene expression and cell signaling pathways.

Related Papers

• → Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment(2009)1,093 cited
• → Artificially induced in situ macrophage polarization: An emerging cellular therapy for immuno-inflammatory diseases(2023)17 cited
• Bone marrow morphology during haematopoietic stem cell mobilisation with cyclophosphamide in mice.(2003)
• Bone marrow morphology during haematopoietic stem cell mobilization with G-CSF in mice.(2004)
• [The role of the hemopoiesis-inducing microenvironment in the postradiation regeneration of hemopoiesis].(1994)