A novel indirect ELISA for diagnosis of dengue fever
The Indian Journal of Medical Research2016Vol. 144(1), pp. 128–133
Citations Over TimeTop 16% of 2016 papers
Rohan Narayan, S. Elaiya Raja, Senthil Kumar, Mohana Sambasivam, Raja Jagadeesan, Kavita Arunagiri, Kaveri Krishnasamy, Gunasekaran Palani
Abstract
The results indicate that the DENV-2 NS5 ELISA is dengue group specific and can be used to differentiate dengue infection from other circulating Flavivirus infections. This NS5 ELISA can also be used to distinguish between primary and secondary dengue fever on the basis of IgM/IgG ratios. Further studies with larger sample sizes and different DENV serotypes are required to validate the ELISA.
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