Targeting Protein–Protein Interactions for Therapeutic Intervention: A Challenge for the Future
Future Medicinal Chemistry2009Vol. 1(1), pp. 65–93
Citations Over TimeTop 10% of 2009 papers
Abstract
Both traditional drug discovery approaches and some more recently developed innovative strategies have already provided valuable tools for the discovery of PPI modulators, and a number of successful examples have highlighted the potential of targeting PPIs for therapeutic intervention, especially in the oncology area.
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