The BTB-ZF transcription factors
Cell Cycle2012Vol. 11(18), pp. 3358–3369
Citations Over TimeTop 11% of 2012 papers
Abstract
The BTB-ZF (broad-complex, tramtrack and bric-à-brac--zinc finger) proteins are encoded by at least 49 genes in mouse and man and commonly serve as sequence-specific silencers of gene expression. This review will focus on the known physiological functions of mammalian BTB-ZF proteins, which include essential roles in the development of the immune system. We discuss their function in terminally differentiated lymphocytes and the progenitors that give rise to them, their action in hematopoietic malignancy and roles beyond the immune system.
Related Papers
- → FOG, a Multitype Zinc Finger Protein, Acts as a Cofactor for Transcription Factor GATA-1 in Erythroid and Megakaryocytic Differentiation(1997)717 cited
- → Tcf7l1 is required for spinal cord progenitor maintenance(2011)11 cited
- → Defining the contribution of Troy -positive progenitor cells to the mouse esophageal epithelium(2024)1 cited
- Fiz1: A Novel Zinc–finger Protein Binds the NRL Transcription Factor Using Internal Domains Different from its RTK–Binding Domains(2004)
- → Faculty Opinions recommendation of The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival.(2003)