Plasma Concentrations of Lidocaine in Dogs Following Lidocaine Patch Application

Citations Over TimeTop 20% of 2007 papers

Abstract

Transdermal absorption of lidocaine was determined by measuring plasma lidocaine concentrations following skin application of 5% lidocaine patches. Two lidocaine patches were placed on the ventral abdominal midline of seven dogs for 72 hours. Lidocaine was detectable in plasma 12 hours after patch application, and it reached steady-state concentrations between 24 and 48 hours. Plasma lidocaine levels decreased dramatically at 60 hours post-application. Low plasma lidocaine concentrations remained for 6 hours after patch removal. No clinically significant side effects were noted.

Related Papers

• → Spray-As-You-Go Airway Topical Anesthesia in Patients with a Difficult Airway: A Randomized, Double-Blind Comparison of 2% and 4% Lidocaine(2009)133 cited
• → Intravenous Lidocaine as a Suppressant of Coughing during Tracheal Intubation(1985)169 cited
• → Intravenous Lidocaine as a Suppressant of Coughing During Tracheal Intubation in Elderly Patients(1993)62 cited
• → Intravenous Lidocaine as a Suppressant of Coughing During Tracheal Intubation in Elderly Patients(1993)7 cited
• → Plasma Concentrations of Lidocaine during Hair Transplantation(1982)15 cited