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Abstract

The aim of this study to compare and evaluate the healing after using N-butyl cyanoacrylate (tissue adhesive) or silk suture on periodontal flap closure. Material and methods: The randomized clinical trial was conducted in Department of Periodontics at Vananchal Dental College and Hospital, Garhwa, Jharkhand, India from January 2021 to January 2022. 50 healthy patients who fulfilled the inclusion and exclusion criteria and were included in this study. Plaque Index (PI), Gingival Index (GI), Wound healing Index (WHI), Histological Assessment (HA)all the study parameters were included in the present study. Results: At baseline postoperative in the suture sites, the mean plaque score was 0.736±0.165 which was reduced to 0.741±0.0997at a 42-day interval. In the cyanoacrylate   sites, the mean plaque score at the baseline recall visit was 0.767±0.1697 and at the 42-day interval, it was 0.738±0.094.  The mean gingival index in the suture sites at the baseline  and42  days interval was 10.688±0.0745 Vs  0.675±0.087 respectively. In the cyanoacrylate   sites, it was 0.6785±0.0744 at the baseline day and 0.675±0.069 at the 42 days follow-up. Wound Healing index score observed at cyanoacrylate sites was also lesser as compared to suture sites with statistical significance at 7th day indicating that wound healing was better when flaps were closed with cyanoacrylate as compared to silk sutures. There was no statistical significance observed between the epithelium of cyanoacrylate and suture sites on 7th and 42nd day. Inflammatory cells at cyanoacrylate sites were lesser as compared to suture sites with statistical significance on the 7th day. Vascularity at cyanoacrylate sites was lesser as compared to suture sites with statistical significance on the 7th day. Conclusion:The closure of periodontal flaps with cyanoacrylate results in better initial post-operative healing as compared to closure with silk suture and that this method of closure can be advocated in a routine surgical periodontal practice