Genotoxic changes in peripheral lymphocytes after therapeutic exposure to crude coal tar and ultraviolet radiation
Biomedical Papers2016Vol. 160(4), pp. 553–558
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Andrea Málková, Renata Köhlerová, Zdeněk Fiala, Květoslava Hamáková, Iva Selke Krulichová, Lenka Borská
Abstract
The elevated levels of the DNA-DSBs and the chromosomal aberrations in the peripheral lymphocytes indicated a genotoxic hazard. However, the elevated level of the chromosomal abnormalities was below the upper level of the reference range for healthy Czech adults. While, the genotoxic risk appears to be low, Goeckerman treatment represents a further contribution to the lifetime load of genotoxic factors.
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