Perineural Invasion and TAMs in Pancreatic Ductal Adenocarcinomas: Review of the Original Pathology Reports Using Immunohistochemical Enhancement and Relationships with Clinicopathological Features
Journal of Cancer2014Vol. 5(9), pp. 754–760
Citations Over TimeTop 17% of 2014 papers
Linjuan Zeng, Yubo Guo, Jianzhong Liang, Shaojie Chen, Peijian Peng, Qiubo Zhang, Hong Su, Yinting Chen, Kaihong Huang
Abstract
TAMs might enhance PNI, and the incidence of PNI was associated with poor prognosis. PNI(+) status and high levels of TAM infiltration further worsen the prognosis. Therapies targeting TAMs might represent auxiliary and preventive treatment for PNI in PDA patients.
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