Nikolaos Zacharakis
National Institutes of Health(US)National Cancer Institute(US)
Publications by Year
Research Areas
CAR-T cell therapy research, Cancer Immunotherapy and Biomarkers, Cancer Genomics and Diagnostics, Immunotherapy and Immune Responses, Virus-based gene therapy research
Most-Cited Works
- → Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer(2018)763 cited
- → Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers(2022)418 cited
- → Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor–Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors(2022)166 cited
- → Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies(2020)153 cited
- → A machine learning model for ranking candidate HLA class I neoantigens based on known neoepitopes from multiple human tumor types(2021)79 cited
- → Phenotypic signatures of circulating neoantigen-reactive CD8+ T cells in patients with metastatic cancers(2023)70 cited
- → Adoptive transfer of personalized neoantigen-reactive TCR-transduced T cells in metastatic colorectal cancer: phase 2 trial interim results(2024)65 cited
- → Using patient-derived tumor organoids from common epithelial cancers to analyze personalized T-cell responses to neoantigens(2023)33 cited
- → Characterization of an Immunogenic Mutation in a Patient with Metastatic Triple-Negative Breast Cancer(2017)32 cited
- → Neoantigen-specific stimulation of tumor-infiltrating lymphocytes enables effective TCR isolation and expansion while preserving stem-like memory phenotypes(2024)28 cited