Matthew J. Stopford
University of Sheffield(GB)
Publications by Year
Research Areas
Amyotrophic Lateral Sclerosis Research, Neurogenetic and Muscular Disorders Research, RNA Research and Splicing, Genetic Neurodegenerative Diseases, Parkinson's Disease Mechanisms and Treatments
Most-Cited Works
- → Micro-RNAs secreted through astrocyte-derived extracellular vesicles cause neuronal network degeneration in C9orf72 ALS(2019)188 cited
- → Antisense RNA foci in the motor neurons of C9ORF72-ALS patients are associated with TDP-43 proteinopathy(2015)170 cited
- → SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits(2017)147 cited
- → Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis(2019)101 cited
- → Invited Review: Decoding the pathophysiological mechanisms that underlieRNAdysregulation in neurodegenerative disorders: a review of the current state of the art(2014)40 cited
- → C9ORF72 hexanucleotide repeat exerts toxicity in a stable, inducible motor neuronal cell model, which is rescued by partial depletion of Pten(2017)29 cited
- → MicroNeurotrophins Improve Survival in Motor Neuron-Astrocyte Co-Cultures but Do Not Improve Disease Phenotypes in a Mutant SOD1 Mouse Model of Amyotrophic Lateral Sclerosis(2016)19 cited
- → High-throughput drug screens for amyotrophic lateral sclerosis drug discovery(2018)18 cited
- → A High-throughput and Pathophysiologically Relevant Astrocyte-motor Neuron Co-culture Assay for Amyotrophic Lateral Sclerosis Therapeutic Discovery(2019)14 cited
- → Inosine reverses motor neuron toxicity observed in amyotrophic lateral sclerosis patient astrocytes with an adenosine deaminase deficiency(2018)1 cited