Nigel Austin
Publications by Year
Research Areas
Receptor Mechanisms and Signaling, Neuroscience and Neuropharmacology Research, Alzheimer's disease research and treatments, Computational Drug Discovery Methods, Neurotransmitter Receptor Influence on Behavior
Most-Cited Works
- → Pharmacological Actions of a Novel, High-Affinity, and Selective Human Dopamine D3 Receptor Antagonist, SB-277011-A(2000)288 cited
- → CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice(2019)236 cited
- → 1,3-Biarylureas as selective non-peptide antagonists of the orexin-1 receptor(2001)165 cited
- → Characterization of a CNS penetrant, selective M1muscarinic receptor agonist, 77‐LH‐28‐1(2008)131 cited
- → Design and Synthesis of trans-N-[4-[2-(6-Cyano-1,2,3,4-tetrahydroisoquinolin-2- yl)ethyl]cyclohexyl]-4-quinolinecarboxamide (SB-277011): A Potent and Selective Dopamine D3 Receptor Antagonist with High Oral Bioavailability and CNS Penetration in the Rat(2000)129 cited
- → Benzazaborinines as Novel Bioisosteric Replacements of Naphthalene: Propranolol as an Example(2015)87 cited
- → Comparison between intraperitoneal and subcutaneous phencyclidine administration in Sprague–Dawley rats: A locomotor activity and gene induction study(2007)79 cited
- → 1,4-Oxazine β-Secretase 1 (BACE1) Inhibitors: From Hit Generation to Orally Bioavailable Brain Penetrant Leads(2015)77 cited
- → Design and Synthesis oftrans-3-(2-(4-((3-(3-(5-Methyl-1,2,4-oxadiazolyl))- phenyl)carboxamido)cyclohexyl)ethyl)-7-methylsulfonyl-2,3,4,5-tetrahydro- 1H-3-benzazepine (SB-414796): A Potent and Selective Dopamine D3Receptor Antagonist(2003)72 cited
- → Integration of Lead Optimization with Crystallography for a Membrane-Bound Ion Channel Target: Discovery of a New Class of AMPA Receptor Positive Allosteric Modulators(2010)66 cited