David M. Duda
Janssen (United States)(US)
Publications by Year
Research Areas
Ubiquitin and proteasome pathways, Enzyme function and inhibition, Autophagy in Disease and Therapy, Protein Degradation and Inhibitors, Cancer-related Molecular Pathways
Most-Cited Works
- → Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation(2008)757 cited
- → Quantitative Proteomics Reveal a Feedforward Mechanism for Mitochondrial PARKIN Translocation and Ubiquitin Chain Synthesis(2014)696 cited
- → Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases(2009)481 cited
- → Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy(2015)310 cited
- → Insights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L Complex(2009)288 cited
- → E2-RING Expansion of the NEDD8 Cascade Confers Specificity to Cullin Modification(2009)271 cited
- → Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation(2016)229 cited
- → Structural regulation of cullin-RING ubiquitin ligase complexes(2011)201 cited
- → Structural and Kinetic Characterization of Active-Site Histidine as a Proton Shuttle in Catalysis by Human Carbonic Anhydrase II,(2005)160 cited
- → E2 conjugating enzymes must disengage from their E1 enzymes before E3-dependent ubiquitin and ubiquitin-like transfer(2005)156 cited