W. Alderton
Publications by Year
Research Areas
Nitric Oxide and Endothelin Effects, Zebrafish Biomedical Research Applications, Receptor Mechanisms and Signaling, Cardiac electrophysiology and arrhythmias, Metal-Catalyzed Oxygenation Mechanisms
Most-Cited Works
- → Nitric oxide synthases: structure, function and inhibition(2001)3,545 cited
- → The Identification of 2-(1H-Indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a Potent, Selective, Orally Bioavailable Inhibitor of Class I PI3 Kinase for the Treatment of Cancer(2008)741 cited
- → Zebrafish: an emerging technology for in vivo pharmacological assessment to identify potential safety liabilities in early drug discovery(2008)271 cited
- → Zebrafish based assays for the assessment of cardiac, visual and gut function — potential safety screens for early drug discovery(2008)187 cited
- → Evaluation of serum CEA, CYFRA21-1 and CA125 for the early detection of colorectal cancer using longitudinal preclinical samples(2015)131 cited
- → Accumulation and metabolism of drugs and CYP probe substrates in zebrafish larvae(2010)109 cited
- → Designer dyes: ‘biomimetic’ ligands for the purification of pharmaceutical proteins by affinity chromatography(1992)105 cited
- → Validation of the use of zebrafish larvae in visual safety assessment(2008)89 cited
- → GW274150 and GW273629 are potent and highly selective inhibitors of inducible nitric oxide synthase in vitro and in vivo(2005)88 cited