James W. Saville
Meso Scale Discovery (United States)(US)
Publications by Year
Research Areas
SARS-CoV-2 and COVID-19 Research, Bacteriophages and microbial interactions, Monoclonal and Polyclonal Antibodies Research, COVID-19 Clinical Research Studies, SARS-CoV-2 detection and testing
Most-Cited Works
- → SARS-CoV-2 Omicron variant: Antibody evasion and cryo-EM structure of spike protein–ACE2 complex(2022)681 cited
- → Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies(2021)198 cited
- → Structural and biochemical rationale for enhanced spike protein fitness in delta and kappa SARS-CoV-2 variants(2022)104 cited
- → Structural analysis of receptor binding domain mutations in SARS-CoV-2 variants of concern that modulate ACE2 and antibody binding(2021)95 cited
- → SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization(2022)65 cited
- → SARS-CoV-2 Omicron Variant: ACE2 Binding, Cryo-EM Structure of Spike Protein-ACE2 Complex and Antibody Evasion(2021)54 cited
- → Allosteric modulation of ryanodine receptor RyR1 by nucleotide derivatives(2023)26 cited
- → Three-Dimensional Visualization of Viral Structure, Entry, and Replication Underlying the Spread of SARS-CoV-2(2022)24 cited
- → Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein(2023)19 cited
- → Altered receptor binding, antibody evasion and retention of T cell recognition by the SARS-CoV-2 XBB.1.5 spike protein(2024)17 cited