Arun Ramamurthy
Takeda (United States)(US)
Publications by Year
Research Areas
Hedgehog Signaling Pathway Studies, Genomics and Chromatin Dynamics, Epigenetics and DNA Methylation, Genetic and rare skin diseases., Neuroscience and Neuropharmacology Research
Most-Cited Works
- → 1-Amino-4-benzylphthalazines as Orally Bioavailable Smoothened Antagonists with Antitumor Activity(2009)106 cited
- → Discovery of NVP‐LEQ506, a Second‐Generation Inhibitor of Smoothened(2013)88 cited
- → Target identification for a Hedgehog pathway inhibitor reveals the receptor GPR39(2014)66 cited
- → Small Molecule Antagonists in Distinct Binding Modes Inhibit Drug-Resistant Mutant of Smoothened(2011)62 cited
- → Identification and structure–activity relationships of ortho-biphenyl carboxamides as potent Smoothened antagonists inhibiting the Hedgehog signaling pathway(2008)35 cited
- → Synthesis of Covalent Probes for the Radiolabeling of the Cannabinoid Receptor(2002)23 cited
- → Chemical Genetic Transcriptional Fingerprinting for Selectivity Profiling of Kinase Inhibitors(2007)5 cited
- → Cover Picture: Discovery of NVP‐LEQ506, a Second‐Generation Inhibitor of Smoothened (ChemMedChem 8/2013)(2013)2 cited
- → Abstract 1322: A cryopreserved allogeneic anti-BCMA CAR-NK cellular therapy exhibits both innate and CAR-mediated MM cell killing in vitro and in vivo(2024)1 cited