Gordon Saxty
Publications by Year
Research Areas
Fibroblast Growth Factor Research, Pharmacogenetics and Drug Metabolism, Inflammatory mediators and NSAID effects, Chemical Synthesis and Analysis, Synthesis and biological activity
Most-Cited Works
- → Identification of N-(4-Piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide (AT7519), a Novel Cyclin Dependent Kinase Inhibitor Using Fragment-Based X-Ray Crystallography and Structure Based Drug Design(2008)337 cited
- → Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor(2017)336 cited
- → Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1:NRF2) Protein–Protein Interaction with High Cell Potency Identified by Fragment-Based Discovery(2016)297 cited
- → Identification of Inhibitors of Protein Kinase B Using Fragment-Based Lead Discovery(2007)138 cited
- → Structure–Activity and Structure–Conformation Relationships of Aryl Propionic Acid Inhibitors of the Kelch-like ECH-Associated Protein 1/Nuclear Factor Erythroid 2-Related Factor 2 (KEAP1/NRF2) Protein–Protein Interaction(2019)92 cited
- → Fragment-Based Discovery of Potent and Selective DDR1/2 Inhibitors(2015)61 cited
- → A Fragment-Derived Clinical Candidate for Antagonism of X-Linked and Cellular Inhibitor of Apoptosis Proteins: 1-(6-[(4-Fluorophenyl)methyl]-5-(hydroxymethyl)-3,3-dimethyl-1 H ,2 H ,3 H -pyrrolo[3,2- b ]pyridin-1-yl)-2-[(2 R ,5 R )-5-methyl-2-([(3R)-3-methylmorpholin-4-yl]methyl)piperazin-1-yl]ethan-1-one (ASTX660)(2018)52 cited
- → Current Trends in Macrocyclic Drug Discovery and beyond -Ro5(2018)30 cited
- → The discovery of quinoline-3-carboxamides as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors(2019)23 cited
- → Macrolide Inspired Macrocycles as Modulators of the IL-17A/IL-17RA Interaction(2021)12 cited