Mihalis S. Kariolis
Denali Therapeutics (United States)(US)
Publications by Year
Research Areas
Cancer Immunotherapy and Biomarkers, Phagocytosis and Immune Regulation, Lysosomal Storage Disorders Research, Cellular transport and secretion, Amyotrophic Lateral Sclerosis Research
Most-Cited Works
- → Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys(2020)340 cited
- → Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET(2014)261 cited
- → Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic(2021)215 cited
- → Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice(2020)197 cited
- → Reprogramming the immunological microenvironment through radiation and targeting Axl(2016)191 cited
- → An engineered Axl 'decoy receptor' effectively silences the Gas6-Axl signaling axis(2014)138 cited
- → Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies(2016)109 cited
- → Molecular architecture determines brain delivery of a transferrin receptor–targeted lysosomal enzyme(2021)82 cited
- → CD98hc is a target for brain delivery of biotherapeutics(2023)80 cited
- → Neutralization of PD-L2 is Essential for Overcoming Immune Checkpoint Blockade Resistance in Ovarian Cancer(2021)58 cited