Jonathan Finlayson
Signature Research (United States)(US)
Publications by Year
Research Areas
Bone Metabolism and Diseases, Antibiotic Resistance in Bacteria, Natural product bioactivities and synthesis, Cyclization and Aryne Chemistry, Tuberculosis Research and Epidemiology
Most-Cited Works
- → The Benzyne Fischer-Indole Reaction(2011)101 cited
- → (1R,2R)-N-(1-Cyanocyclopropyl)-2-(6-methoxy-1,3,4,5-tetrahydropyrido[4,3-b]indole-2-carbonyl)cyclohexanecarboxamide (AZD4996): A Potent and Highly Selective Cathepsin K Inhibitor for the Treatment of Osteoarthritis(2012)39 cited
- → Pharmacokinetic Benefits of 3,4-Dimethoxy Substitution of a Phenyl Ring and Design of Isosteres Yielding Orally Available Cathepsin K Inhibitors(2012)22 cited
- → Discovery and structure–activity relationships of a novel oxazolidinone class of bacterial type II topoisomerase inhibitors(2022)14 cited
- → The discovery of N-cyclopropyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3(4H)-yl]benzamide (AZD6703), a clinical p38α MAP kinase inhibitor for the treatment of inflammatory diseases(2012)11 cited
- → Synthesis of Indole-Dihydroisoquinoline Sulfonyl Ureas via Three-Component Reactions(2018)6 cited
- → Isosteric replacements for benzothiazoles and optimisation to potent Cathepsin K inhibitors free from hERG channel inhibition(2012)5 cited
- → Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors(2023)4 cited
- → Abstract B118: Through hit synergy and beyond! Integrating hit finding and direct to biology to shorten time to development candidate(2025)
- → ChemInform Abstract: The Benzyne Fischer‐Indole Reaction.(2011)