C. John Blankley
Massachusetts Institute of Technology(US)
Publications by Year
Research Areas
Lipoproteins and Cardiovascular Health, Cholesterol and Lipid Metabolism, Computational Drug Discovery Methods, Receptor Mechanisms and Signaling, Cancer, Lipids, and Metabolism
Most-Cited Works
- → Inhibitors of cholesterol biosynthesis. 3. Tetrahydro-4-hydroxy-6-[2-(1H-pyrrol-1-yl)ethyl]-2H-pyran 2-one inhibitors of HMG-CoA reductase. 2. Effects of introducing substituents at positions three and four of the pyrrole nucleus(1991)183 cited
- → Synthesis and structure-activity relationships of a novel series of non-peptide angiotensin II receptor binding inhibitors specific for the AT2 subtype(1991)161 cited
- → Antihypertensive activity of 6-arylpyrido[2,3-d]pyrimidin-7-amine derivatives(1981)110 cited
- → Synthesis of novel angiotensin converting enzyme inhibitor quinapril and related compounds. A divergence of structure-activity relationships for non-sulfhydryl and sulfhydryl types(1986)82 cited
- → Preparation and decomposition of unsaturated esters of diazoacetic acid(1968)74 cited
- → Inhibitors of acyl-CoA:cholesterol acyltransferase. 1. Identification and structure-activity relationships of a novel series of fatty acid anilide hypocholesterolemic agents(1992)67 cited
- → Relationship between tissue selectivity and lipophilicity for inhibitors of HMG-CoA reductase(1991)59 cited
- → Inhibitors of acyl-CoA:cholesterol acyltransferase. 4. A novel series of urea ACAT inhibitors as potential hypocholesterolemic agents(1993)54 cited
- → Prediction of blood-brain partitioning using Monte Carlo simulations of molecules in water(2001)50 cited
- → Inhibitors of Acyl-CoA:Cholesterol O-Acyl Transferase (ACAT) as Hypocholesterolemic Agents. 8. Incorporation of Amide or Amine Functionalities into a Series of Disubstituted Ureas and Carbamates. Effects on ACAT Inhibition in vitro and Efficacy in vivo(1994)47 cited