Dwight Macdonald
Publications by Year
Research Areas
Phosphodiesterase function and regulation, Cholinesterase and Neurodegenerative Diseases, Receptor Mechanisms and Signaling, Asymmetric Synthesis and Catalysis, European history and politics
Most-Cited Works
- → Deletion of phosphodiesterase 4D in mice shortens α2-adrenoceptor–mediated anesthesia, a behavioral correlate of emesis(2002)266 cited
- Against the American grain(1962)
- → The next generation of PDE4 inhibitors(2001)118 cited
- → A triply convergent enantioselective total synthesis of (+)-ikarugamycin(1989)76 cited
- → Total synthesis of (+)-ikarugamycin. 2. Elaboration of the macrocyclic lactam and tetramic acid substructures and complete assembly of the antibiotic(1990)49 cited
- → Discovery of MK-0952, a selective PDE4 inhibitor for the treatment of long-term memory loss and mild cognitive impairment(2010)43 cited
- → Process Development and Large-Scale Synthesis of a PDE4 Inhibitor(2005)39 cited
- → Thiopyranol[2,3,4-c,d]indoles as Inhibitors of 5-Lipoxygenase, 5-Lipoxygenase-Activating Protein, and Leukotriene C4 Synthase(1995)38 cited