Stephen P. Jacober
Boehringer Ingelheim (Canada)(CA)
Publications by Year
Research Areas
Cytokine Signaling Pathways and Interactions, DNA and Nucleic Acid Chemistry, Carbohydrate Chemistry and Synthesis, NF-κB Signaling Pathways, Advanced Chemical Physics Studies
Most-Cited Works
- → Evolution of the Thienopyridine Class of Inhibitors of IκB Kinase-β: Part I: Hit-to-Lead Strategies(2006)67 cited
- → Discovery of 2-Phenylamino-imidazo[4,5-h]isoquinolin-9-ones: A New Class of Inhibitors of Lck Kinase(2002)63 cited
- → Crystal structure of nevirapine, a non-nucleoside inhibitor of HIV-1 reverse transcriptase, and computational alignment with a structurally diverse inhibitor(1992)53 cited
- → Inhibition of human leukocyte elastase (HLE) by N-substituted peptidyl trifluoromethyl ketones(1992)48 cited
- → Metal-coordination, hydrogen-bond network formation, and protein-solvent interactions in native and complexed human carbonic anhydrase I: a molecular mechanics study(1989)46 cited
- → elastase inhibitors containing conformationally restricted lactams as P3-P2 dipeptide replacements(1993)41 cited
- → Reversible binding of peptide aldehydes to papain. Structure-activity relationships(1991)37 cited
- → Inhibition of human leukocyte elastase by N-substituted peptides containing .alpha.,.alpha.-difluorostatone residues at P1(1992)27 cited
- → Carbon-13 and oxygen-18 kinetic isotope effects on methanolysis of p-nitrostyrene oxide(1986)14 cited
- → Comparison of the toxicity of methylcyclopentadienyl manganese tricarbonyl with that of its two major metabolites(1987)10 cited