Vincent Galullo
AstraZeneca (United States)(US)
Publications by Year
Research Areas
Cancer therapeutics and mechanisms, Antibiotic Resistance in Bacteria, Antibiotics Pharmacokinetics and Efficacy, Synthesis and biological activity, Melanoma and MAPK Pathways
Most-Cited Works
- → The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase(1997)275 cited
- → A single amino acid substitution makes ERK2 susceptible to pyridinyl imidazole inhibitors of p38 MAP kinase(1998)135 cited
- → Cellular and biochemical characterization of VX-710 as a chemosensitizer(1997)130 cited
- → Novel N-Linked Aminopiperidine Inhibitors of Bacterial Topoisomerase Type II: Broad-Spectrum Antibacterial Agents with Reduced hERG Activity(2011)101 cited
- → Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases(2015)100 cited
- → The Discovery of VX-745: A Novel and Selective p38α Kinase Inhibitor(2011)83 cited
- → Discovery of Novel DNA Gyrase Inhibiting Spiropyrimidinetriones: Benzisoxazole Fusion with N-Linked Oxazolidinone Substituents Leading to a Clinical Candidate (ETX0914)(2015)70 cited
- → Novel DNA Gyrase Inhibiting Spiropyrimidinetriones with a Benzisoxazole Scaffold: SAR and in Vivo Characterization(2014)56 cited
- → Discovery of Efficacious Pseudomonas aeruginosa-Targeted Siderophore-Conjugated Monocarbams by Application of a Semi-mechanistic Pharmacokinetic/Pharmacodynamic Model(2015)26 cited
- → Synthesis of a Tetrahydronaphthyridine Spiropyrimidinetrione DNA Gyrase Inhibiting Antibacterial Agent - Differential Substitution at all Five Carbon Atoms of Pyridine.(2014)25 cited