Ilaria Tassi
Alector (United States)(US)
Publications by Year
Research Areas
Immune Cell Function and Interaction, T-cell and B-cell Immunology, Neuroinflammation and Neurodegeneration Mechanisms, Inflammation biomarkers and pathways, Neurological Disease Mechanisms and Treatments
Most-Cited Works
- → Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer’s disease model(2020)538 cited
- → TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis(2020)360 cited
- → Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and β-catenin(2009)310 cited
- → Identification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammation(2008)308 cited
- → IL-17 drives psoriatic inflammation via distinct, target cell-specific mechanisms(2014)168 cited
- → The Cytotoxicity Receptor CRACC (CS-1) Recruits EAT-2 and Activates the PI3K and Phospholipase Cγ Signaling Pathways in Human NK Cells(2005)122 cited
- → Phospholipase C-γ2 Is a Critical Signaling Mediator for Murine NK Cell Activating Receptors(2005)118 cited
- → Differential Requirements for Vav Proteins in DAP10- and ITAM-mediated NK Cell Cytotoxicity(2004)117 cited
- → p110γ and p110δ Phosphoinositide 3-Kinase Signaling Pathways Synergize to Control Development and Functions of Murine NK Cells(2007)103 cited
- → Preclinical and first-in-human evaluation of AL002, a novel TREM2 agonistic antibody for Alzheimer’s disease(2024)74 cited